Downloadable Resources
Tepkinly Preparation and Administration
A guide to the dilution and preparation of the priming (0.16mg), intermediate (0.8mg) doses, and the preparation of the full dose (48mg) of Tepkinly for subcutaneous administration. View the video for a full run through on storage, handling and preparation of Tepkinly, indicated as monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma (DLBCL) after two or more lines of systemic therapy.1
Tepkinly Mode of Action animation
The Tepkinly mechanism of action is explained in this video which shows how by binding simultaneously to CD3 on T cells and CD20 on B cells, epcoritamab forms an immune synapse – inducing cytokine release and T-cell–mediated killing of malignant CD20-expressing cells.1
References
- Tepkinly Summary of Product Characteristics.
UK-EPCOR-240327. Date of preparation: September 2024.
Adverse events should be reported. Reporting forms and information can be found at yellowcard.mhra.gov.uk.
Adverse events should also be reported to AbbVie on GBPV@abbvie.com