Manage-PD
Understanding MANAGE-PD with Prof. Angelo Antonini
Leading international neurologist Prof. Angelo Antonini from the Parkinson’s and Movement Disorders Unit at the Department of Neuroscience, University of Padua, Italy, discusses the development and validation of the Manage-PD tool, and how it helps to address the unmet needs in current aPD management. (19:30 mins)
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What is the Manage-PD tool and how can it help you in your practice?
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How the tool was developed: Using the mixed method approach.
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Overview of the Manage-PD tool. How to navigate the different sections.
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Using the scoring algorithm to categorise patients.
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The three scoring categories: Controlled; not controlled; and not controlled and who may benefit from device-assisted therapy.
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Vignette-based method for tool development.
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Concordance in identifying patients with inadequate PD symptom control.
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Patient validation of the Manage-PD tool: Real-world evidence.
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Conclusions and summary.
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MANAGE-PD builds on the Delphi consensus criteria* to create a clinically useful tool1
*Taking oral levodopa ≥ 5 times daily, ≥ 2 hours of OFF time/day, presence of unpredictable fluctuations of motor symptoms, presence of troublesome dyskinesia, and limitations in ≥ 1 activity of daily living.2
All content is intended only for informational use by licensed healthcare professionals and is not offered as or intended to be medical advice for any particular patient. This information is not intended for patients.
Only a healthcare professional exercising independent clinical judgment can make decisions regarding appropriate patient care and treatment options considering the unique characteristics of each patient.
MANAGE-PD is a screening tool intended to be used by healthcare professionals (HCPs). This tool is aiming to support HCP’s decision-making for the timely management of Parkinson’s disease symptoms based on comprehensive evaluation of frequency and severity of the motor, non-motor and functional symptoms.
This questionnaire consists of two parts: Section 1 and Section 2. Symptoms should be assessed based on the previous 1 month. This tool does not give guidance concerning the type of device-aided therapy, but gives an indication that this type of therapy can be considered. Use of the AbbVie name, its logos, their trademarks, trade names or trade dress is prohibited without the prior written authorisation of AbbVie, except to identify the product or services of AbbVie. The Parkinson’s Foundation logo is the sole property of the Parkinson’s Foundation. Any use of the Parkinson’s Foundation name or logo without Foundation permission is prohibited.
Manage-PD is a collaborative research and development effort between AbbVie Inc. Medical Affairs and Health Economics and Outcomes, the Parkinson’s Foundation and an international panel of movement disorder specialists.
Abbreviation: MDS; Movement disorder specialist. aPD; advanced Parkinson’s disease.
References: 1. Antonini A, et al. Parkinsonism Relat Disord 2021 Nov;92:59-66. 2. Antonini A et al. Curr Med Res Opin 2018;34(12):2063–2073. 3. Antonini A et al. (2019) 23rd Annual International Congress of Parkinson’s Disease and Movement Disorders. Nice, France. Abstract 2142. 4. Antonini A et al. 2019. Poster presented at AAN, Philadelphia, PA. May 4–10, 2019.
AU-NEUP-230059. June 2024.